CasNo： 374675-21-5
Molecular Formula： C63H83 N17 O14
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KISSPEPTIN-10 is , while it's Molecular Formula is C63H83 N17 O14. Metastin (45-54) is a potent and selective agonist of AXOR12 and hOT7T175.
The CAS number of KISSPEPTIN-10 is 374675-21-5.
More information of KISSPEPTIN-10 374675-21-5 are:
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Synonyms |
16:PN: WO2004063221 SEQID: 16 claimed protein; 16: PN: WO2007072997 SEQID: 16claimed protein; 6: PN: WO03027149 SEQID: 6 claimed protein; Human kiss-10F;Human kisspeptin 10F; Human metastin 45-54; Kisspeptin-10 (human) |
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CAS Number |
374675-21-5 |
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Molecular Formula |
C63H83 N17 O14 |
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Molecular Weight |
1302.44 |
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Density |
1.46±0.1 g/cm3(Predicted) |
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PSA |
535.34000 |
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LogP |
3.51400 |
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Pka |
9.96±0.15(Predicted) |
Metastin (45-54) is a 10 amino acid peptide that corresponds to the bioactive C-terminal 45-54 amino acids of metastin, a metastasis suppressor gene product. It acts as a potent agonist of GPR54 (OT7T175, AXOR12), with approximately 8-fold higher binding affinity than metastin (Ki values of 0.042 and 0.34 nM, respectively, for displacement of metastin (40-54)). Metastin (45-54) induces calcium mobilization in GPR54-transfected cells (EC50 = 0.18-1.1 nM). It inhibits the migration of GPR54-transfected CHO cells at concentrations of 10-100 nM, equaling the potency of full length metastin.
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